Primary immune (PI) deficiency is an inherited deficiency of the immune system. Primary immune deficiency is not the one that is acquired but found during the birth. AIDS are the ones that are acquired but not primary immune deficiency. AIDS come under the acquired immune deficiency category.

Surveys indicate that around 25000 to 50000 people in the United States suffer from primary immune deficiency diseases. There are more than 80 different types of primary immune deficiency diseases found. We know that our immune system has many different types of cells. A deficiency in different combinations of the immune cells that have been inherited during birth gives way to many different PI deficiency diseases. Some of the PI diseases show no symptoms at all if they are not severe, while other primary immune deficiency diseases which are severe shows symptoms.

It is found that more boys are affected by these diseases than girls. The primary immune deficiency symptoms occur during infancy or later in the childhood stage of the life.If a person is suspected of having a primary immune deficiency he is tested for that with many screening tests. If it is found that the function of the immune system is not normal then a clinical immunologist is consulted to find out the type of primary immune deficiency.

In some cases pulmonologists, rheumatologists, gastroenterologists, and hematologists are also consulted to identify the type of primary immune deficiency and the ways to treat it. Some of the PI diseases are IgA deficiency, Common Variable Immunodeficiency (CVI), X-Linked Agammaglobulinemia (XLA), Severe Combined Immunodeficiency (SCID), Chronic Granulomatous Disease (CGD), Hyper-IgM Syndrome, Interferon-Gamma Receptor (IFNGR) Deficiency, Hyper-IgE (HIE) Syndrome, and Leukocyte Adhesion Deficiency (LAD).

 

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